Long After Her Gastric Bypass Surgery, This Woman’s Weight Loss Wouldn’t Stop

This write-up appeared in the July/August 2021 challenge of Discover magazine as “Slender to None.” Subscribe for more tales like these.


Ann was a extensive-standing client of mine whom I saw for critical gastroesophageal reflux illness, also known as GERD. She was incredibly overweight and achieved medical criteria for morbid being overweight. Health professionals take into consideration a client morbidly obese when they are at the very least 100 lbs about their best entire body weight — and/or when their weight may appreciably add to medical disorders, like diabetic issues, higher blood tension, or fatty liver illness, that place their everyday living in danger. Ann was five toes 4 inches tall and weighed 250 lbs. She experienced been a trim one hundred thirty-pound athlete as a teen, but experienced acquired weight with every single of her pregnancies.

All through a person of our clinic visits, the matter of her probably going through surgical procedures to lose weight came up. I was supportive of Ann observing a surgeon who specialized in this area. These kinds of procedures, known as bariatric surgical procedures, have grow to be incredibly well-known with patients, provided their higher achievement fees and the normally spectacular and everyday living-switching outcomes that they can produce.

Many bariatric surgical procedures exist, but following meeting with our surgeon, Ann experienced made a decision to go through a distinct bariatric method known as a Roux-en-Y gastric bypass. This distinct operation normally outcomes in the most spectacular and strong weight decline for patients. The surgical procedures involves the creation of a compact “pouch” designed from a part of the stomach. This pouch can only keep a compact sum of foodstuff at a provided time and is related to a section of compact intestine. The remaining part of the stomach, which is related to the top rated of the compact bowel, is basically remaining in place.

But following the method, ingested foodstuff no for a longer time flows as a result of these regions of the gastrointestinal tract this is the “bypass” that is referred to in the operation’s identify. Food that is swallowed bypasses the starting of the compact intestine and enters the bowel, where it is digested a lot further down the line. Right after this surgical procedures, patients lose weight by a number of means. For a person, the surgical procedures restricts how a lot they can try to eat at a provided time simply because the pouch is so compact compared to a normal stomach. Further than that, a lot of the compact bowel, where foodstuff is normally absorbed, by no means sees ingested foodstuff anymore. As a bonus, the Roux-en-Y gastric bypass is also incredibly efficient at managing GERD. Ann underwent the surgical procedures with no any troubles.

The to start with 12 months following the surgical procedures was a incredibly thrilling time for Ann. She lost nearly seventy five lbs, her self-graphic soared, and she handled herself to an totally new wardrobe. Victory, it appeared, was at hand.

Unforeseen Difficulties

I was hence understandably stunned to see Ann back in my clinic just 3 months following her a person-12 months surgical anniversary. Hunting troubled, she instructed me that she felt weak and weary all the time. She experienced recognized a myriad of new difficulties, which include vision variations and quick bruising, with even minor bumps ensuing in hideous purple blotches on her arms and legs. Most relating to, Ann’s weight decline was continuing further than the stage that would be anticipated next a gastric bypass. She experienced now lost about 100 lbs and experienced long gone from wanting sturdy to, rather frankly, sickly. Most patients encounter a weight-decline plateau at about the a person-12 months mark, but Ann’s weight experienced ongoing to decline.

Ann was very seriously apprehensive she experienced produced a cancerous tumor that would clarify her weight decline — a not-unreasonable fear. But a CT scan of her stomach and pelvis did not disclose any obvious abnormalities. I also performed an higher endoscopy and a colonoscopy on Ann to make certain nothing was amiss with her gastric bypass and to further make certain she did not have colon cancer the procedures unsuccessful to expose something that may possibly clarify her weight decline. But blood checks that I performed confirmed that Ann was struggling from major malnutrition. In addition, her quick bruising prompted me to verify her vitamin ranges, given that vitamin K deficiency is commonly related with bruising. Her vitamin K amount was incredibly very low, as was her vitamin A amount.

Now we also experienced an solution for her vision variations, as vitamin A is necessary for healthy vision. Each vitamin K and A are among the so-referred to as “fatsoluble” vitamins, this means that they don’t dissolve in drinking water, but in extra fat. Vitamin A and K deficiencies are scarce, and Ann was getting a multivitamin that incorporated the two of these. This recommended that Ann’s intake of the vitamins themselves was ample, but her entire body basically wasn’t absorbing enough of the vitamins they contained.

System Breakdown

When I asked Ann if she was owning diarrhea, she explained she was owning up to 4 bowel movements per working day. I asked her if her stools looked oily or greasy. Her eyes widened and she nodded. “I have not instructed anybody that nonetheless,” she explained. The medical phrase for greasy stools is steatorrhea, and the existence of extra fat in stool is relating to. The human entire body is incredibly successful at absorbing extra fat from foodstuff, probable reflecting previously eras when extra fat was a scarce dietary commodity. Fat in the stool, however, is a telltale sign that the entire body is not able to take in ingested foodstuff appropriately. Fat-soluble vitamins are absorbed passively by the entire body together with ingested extra fat, but if you cannot take in extra fat, you cannot take in extra fat-soluble vitamins, and deficiencies will establish.

Although most individuals assume their stomach digests their foodstuff, it’s truly the pancreas that does most of the do the job. The pancreas creates enzymes that crack down carbs, fat, and proteins into their standard making blocks, which the compact intestine can then take in. Steatorrhea is most typically observed in patients with long-term pancreatitis. That condition normally develops thanks to liquor abuse, genetic things, or other leads to. In these patients, the pancreas results in being scarred and atrophic and can no for a longer time make or launch enough pancreatic enzymes.

The pancreas is normally accountable for digesting foodstuff.(Credit rating: Kellie Jaeger/Discover)

But Ann did not have long-term pancreatitis — her CT scan experienced shown a normal pancreas. Even now, I began to wonder if Ann was struggling from asynchrony. Asynchrony can at times establish following sophisticated bowel reconstructions, which include a Rouxen-Y gastric bypass. In order for normal digestion to come about, all pieces of the intestine not only have to do the job the ideal way, but also at the ideal time and in the ideal place, like a finely choreographed ballet. Ann’s gastric bypass meant that her foodstuff was going down a person limb of compact bowel, but her pancreas was dumping digestive enzymes into another, and there was no foodstuff going as a result of that area at all. As a outcome, the foodstuff was not interacting with the enzymes that have been necessary to crack it down. Her entire body was basically passing undigested foodstuff as a result of her.

I gave Ann a prescription for pancreatic enzymes— pills that contains digestive enzymes attained from pigs, consider it or not. When taken with a meal, these enzymes activate and crack down foodstuff just like enzymes from a human pancreas. Then, the compact intestine can take in these lesser molecules. Inside a couple of times of beginning the treatment, Ann’s stools experienced normalized and her weight decline stopped. A blood examination attained a couple of weeks afterwards confirmed that her vitamin ranges have been on the rise.

Ann would need to have to choose supplemental enzymes for the rest of her everyday living, so her entire body could sustain a desirable weight and her absorption of foodstuff would be normal. She was not satisfied about the added pills, but they worked. The gastric bypass giveth, and the gastric bypass taketh away.


Douglas G. Adler is co-director of the Middle for Sophisticated Therapeutic Endoscopy in Denver. The situations described in Important Signs are authentic, but names and selected facts have been modified.